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The Marlins are road underdogs (+126) against the Pirates (-152). The Pittsburgh Pirates will give the start to Bailey Falter (4-3, 3.49 ERA), who is looking for win No. 5 on the season, and the Marlins will counter with Cal Quantrill (3-6, 5.63 ERA).

Adam Frazier and Andrew McCutchen each had three hits and an RBI, and Bryan Reynolds had two hits including a bases-clearing triple to help the host Pittsburgh Pirates top the Miami Marlins 10-3 on Monday night.

Sandy Alcantara struck out six in six shutout innings, and the Miami Marlins edged the Pittsburgh Pirates 3-2.

SportsLine's model simulated Pittsburgh Pirates vs. Miami Marlins 10,000 times and revealed its MLB picks for Wednesday afternoon's matchup at PNC Park in Pittsburgh

It’s Tuesday, June 10 and the Marlins (24-40) are in Pittsburgh to take on the Pirates (27-40). Sandy Alcantara is slated to take the mound for Miami against Mitch Keller for Pittsburgh.

The Miami Marlins (24-39) and the Pittsburgh Pirates (26-40) open a 3-game series Monday. First pitch from PNC Park is at 6:40 p.m. ET (FS1). Let's analyze BetMGM Sportsbook's MLB odds around the Marlins vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

Preview the June 11 matchup between the Pittsburgh Pirates and Miami Marlins with odds over/under, game spread, betting lines and more.