SportsLine expert Eric Cohen has revealed his best bets for Clemson Tigers vs. LSU Tigers as Lane Kiffin makes his LSU debut in Week 1

No. 19 SMU and Florida State take center stage on Labor Day. Led by star quarterback Kevin Jennings, the ACC active leader in career passing yards (7,709) and career total yards (8,267), SMU finds itself in the preseason top 20 for the second straight year.

The Clemson Tigers visit the LSU Tigers on Saturday, September 5, in week 1 of the 2026-27 college football season.

LSU kicks off the Lane Kiffin era against a familiar foe in Clemson in each team's 2026 college football Week 1 opener

The biggest game of Week 1 is undoubtedly Clemson traveling to play No. 11 LSU in Baton Rouge, which many consider to be the most electric atmosphere in the country.  Nov 29, 2025; Columbia, South Carolina,

Lane Kiffin’s first game as LSU’s head coach was always going to attract attention, but his glamorous arrival at Tiger Stadium took the spotlight to another level. The Tigers welcomed nearly 900 media and celebrity guests for the Clemson matchup in Week 1 of the 2026 college football season,

We offer some college football trades you can make for the 2026 Week 1 Clemson vs. LSU matchup at Kalshi and Polymarket

Looking for value in tonight's Week 1 main event? Our Clemson vs. LSU expert picks & prediction details why defensive dominance and offensive growing pains make the Under a smash play at Tiger Stadium on Saturday,